TY  - EJOU
AU  - Ali, A. Lina Haj
AU  - Dăniluc, D. Larissa
AU  - Suhov, S. Loredana
AU  - Pecingina, P. Radu
AU  - Viviana Ivan, V. Mihaela
TI  - Cardiovascular Implications of COVID-19 and the QT Prolongation Associated with Pharmacotherapy
T2  - Journal of Experimental Pharmacology and Toxicology

PY  - 2025
VL  - 1
IS  - 1
SN  - 3091-0595

AB  - The coronavirus pandemic has significantly impacted a substantial part of the global population, and the cardiovascular repercussions of COVID-19 infection have been unveiled for the first time. While the arrhythmogenic effects of the severe inflammatory syndrome associated with the infection are well-established, another critical cause of arrhythmias, particularly ventricular arrhythmias such as ventricular tachycardia, torsades de pointes, or ventricular fibrillation, which can result in cardiac arrest, is the pharmacological treatment employed to manage the disease in hospitalized patients. Among all arrhythmogenic mechanisms, the QT interval prolongation is the most alarming. This review aims to provide a more in-depth exploration of these effects and the potential mechanisms underlying their occurrence.
KW  - COVID-19
KW  - pharmacotherapy
KW  - QT prolongation
KW  - arrhythmias
DO  - 10.6425/012025jept004