@Article{
AUTHOR = {Dinu, Ștefania Dinu and Moldoveanu, Adrian Moldoveanu and Szuhanek, Camelia Szuhanek and Milutinovici, Raluca Milutinovici and Ali, Diana Haj Ali and Talpoș, Șerban Talpoș},
TITLE = {Hydroxyapatite in Contemporary Dentistry: Functional Versatility, Formulation Advances, and Clinical Relevance},
JOURNAL = {Journal of Experimental Pharmacology and Toxicology},
VOLUME = {2},
YEAR = {2025},
NUMBER = {2},
PAGES = {0--0},
URL = {https://j-pharmacol-tox-exp.com/article/2/2/20},
ISSN = {3091-0595},
ABSTRACT = {1. Background/Objectives: Calcium phosphate biomaterials (CPBs), including hydroxyapatite (HA), are among the most commonly used biomaterials in dentistry due to their biocompatibility and similarity to the body’s hard tissues. This review aims to highlight the clinical applications of CPBs in dentistry, focusing mainly on hydroxyapatite and its modern formulations. 2. Methods: A literature search was conducted by analyzing data published up to May 2025 in databases such as PubMed, Web of Science, and Google Scholar using keyword combinations such as “Biomaterials”, “dentistry”, “calcium phosphate”, and “hydroxyapatite”. 3. Results: The findings of this work reveal the wide clinical use of HA, including tooth remineralization, implant coating, bone grafting, and the treatment of dental hypersensitivity. Furthermore, the novel formulations of hydroxyapatite have substantially improved its therapeutic and physicochemical characteristics. 4. Conclusions: The clinical relevance of HA and its modern formulations emphasizes the need for continuous research that will contribute to further enhancement of HA’s therapeutic outcomes.},
DOI = {10.6425/022025jept005}
}