%0 Journal Article
%A Căpraru, Anca-Maria Căpraru
%A Ardelean, Simona Ardelean
%A Zurbău-Anghel, Nicoleta Zurbău-Anghel
%A Dărăban, Adriana Maria Dărăban
%A Munteanu, Melania Munteanu
%A Rusu, Andreea Ioana Rusu
%D 2025
%J Journal of Experimental Pharmacology and Toxicology

%@ 3091-0595

%V 2
%N 2
%P 6

%T Vitamin D as a Preventive and Therapeutic Agent in Cervical Cancer: Insights from Clinical Studies
%M doi:10.6425/022025jept006
%U https://j-pharmacol-tox-exp.com/article/2/2/21
%X Cervical cancer remains a significant global health issue, closely linked to persistent human papillomavirus (HPV) infections. Vitamin D, recognized primarily for its role in calcium homeostasis and bone metabolism, has emerged as a promising preventive and therapeutic agent in cancer management. Recent clinical studies have suggested that vitamin D may effectively prevent cervical cancer and aid in the regression of early cervical dysplasia (CIN 1 orc LSIL). However, its therapeutic impact appears limited for advanced cervical dysplasia (CIN 2/3, HSIL) and established cervical cancer cases. Due to the progressive nature of cervical lesions, vitamin D supplementation represents a potentially valuable strategy for secondary prevention. This review critically evaluates current clinical evidence, underscores key insights into vitamin D’s role in cervical cancer management, and highlights existing gaps requiring further research.